Vector-Borne Diseases: Environmental, Human Health, and Ecological Connections

August 23, 2017




Vector-borne diseases are illnesses caused by pathogens and parasites in human populations. Every year there are more than 1 billion cases and over 1 million deaths from vector-borne diseases such as malaria, dengue, schistosomiasis, human African trypanosomiasis, leishmaniasis, Chagas disease, yellow fever, Japanese encephalitis and onchocerciasis, globally.

Vector-borne diseases account for over 17% of all infectious diseases.



Main vectors and diseases they transmit

Vectors are living organisms that can transmit infectious diseases between humans or from animals to humans. Many of these vectors are bloodsucking insects, which ingest disease-producing microorganisms during a blood meal from an infected host (human or animal) and later inject it into a new host during their subsequent blood meal.

Mosquitoes are the best known disease vector. Others include ticks, flies, sandflies, fleas, triatomine bugs and some freshwater aquatic snails.

Mosquitoes

  • Aedes
    • Chikungunya
    • Dengue fever
    • Rift Valley fever
    • Yellow fever
    • Zika
  • Anopheles
    • Malaria
  • Culex
    • Japanese encephalitis
    • Lymphatic filariasis
    • West Nile fever

Sandflies

  • Leishmaniasis
  • Sandfly fever (phelebotomus fever)

Ticks

  • Crimean-Congo haemorrhagic fever
  • Lyme disease
  • Relapsing fever (borreliosis)
  • Rickettsial diseases (spotted fever and Q fever)
  • Tick-borne encephalitis
  • Tularaemia

Triatomine bugs

  • Chagas disease (American trypanosomiasis)

Tsetse flies

  • Sleeping sickness (African trypanosomiasis)

Fleas

  • Plague (transmitted by fleas from rats to humans)
  • Rickettsiosis

Black flies

  • Onchocerciasis (river blindness)

Aquatic snails

  • Schistosomiasis (bilharziasis)

The World Health Organization (WHO) states that control and prevention of vector-borne diseases are emphasizing "Integrated Vector Management (IVM)",which is an approach that looks at the links between health and environment, optimizing benefits to both.
In April 2014, WHO launched a campaign called “Small bite, big threat” to educate people about vector-borne illnesses. WHO issued reports indicating that vector-borne illnesses affect poor people, especially people living in areas that do not have adequate levels of sanitation, drinking water and housing.



For diseases where there is no effective cure, such as Zika Virus, West Nile Virus and Dengue fever, vector control remains the only way to protect human populations.

However, even for vector-borne diseases with effective treatments the high cost of treatment remains a huge barrier to large amounts of developing world populations. Despite being treatable, malaria has by far the greatest impact on human health from vectors. In Africa, a child dies every minute of malaria; this is a reduction of more than 50% since 2000 due to vector control. In countries where malaria is well established the World Health Organization estimates countries lose 1.3% annual economic income due to the disease. Both prevention through vector control and treatment are needed to protect populations.
As the impacts of disease and virus are devastating, the need to control the vectors in which they carried is prioritized. Vector control in many developing countries can have tremendous impacts as it increases mortality rates, especially among infants. Because of the high movement of the population, disease spread is also a greater issue in these areas.
As many vector control methods are effective against multiple diseases, they can be integrated together to combat multiple diseases at once.[5] The World Health Organization therefore recommends "Integrated Vector Management" as the process for developing and implementing strategies for vector control.

Methods
Vector control focuses on utilizing preventative methods to control or eliminate vector populations. Common preventative measures are:

Habitat and environmental control
Removing or reducing areas where vectors can easily breed can help limit their growth. For example, stagnant water removal, destruction of old tires and cans which serve as mosquito breeding environments, and good management of used water can reduce areas of excessive vector incidence.
Further examples for environmental control is by reducing the prevalence of open defecation or improving the designs and maintenance of pit latrines. This can reduce the incidence of flies acting as vectors to spread diseases via their contact with feces of infected people.

Reducing contact
Limiting exposure to insects or animals that are known disease vectors can reduce infection risks significantly. For example, bed nets, window screens on homes, or protective clothing can help reduce the likelihood contact with vectors. To be effective this requires education and promotion of methods among the population to raise the awareness of vector threats.

Chemical control
Insecticides, larvicides, rodenticides, Lethal ovitraps and repellents can be used to control vectors. For example, larvicides can be used in mosquito breeding zones; insecticides can be applied to house walls or bed nets, and use of personal repellents can reduce incidence of insect bites and thus infection. The use of pesticides for vector control is promoted by the World Health Organization (WHO) and has proven to be highly effective.

Biological control
The use of natural vector predators, such as bacterial toxins or botanical compounds, can help control vector populations. Using fish that eat mosquito larvae or reducing breeding rates by introducing sterilized male tsetse flies have been shown to control vector populations and reduce infection risks.

Legislation
In the United States, cities or special districts are responsible for vector control. For example, in California, the Greater Los Angeles County Vector Control District is a special district set up by the state to oversee vector control in multiple cities.
 


References
"Vector". WordNet Search 3.1. Princeton University. Retrieved 7 April 2014.
"WHO Malaria". World Health Organization. 2015.

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